Saturday, Sep 19, 2020 | Last Update : 10:13 PM IST

179th Day Of Lockdown

Maharashtra114584081235431351 Andhra Pradesh6095585198915244 Tamil Nadu5309084757178685 Karnataka5029823940257808 Uttar Pradesh3362942632884771 Delhi2347011981034877 West Bengal2155801870614183 Odisha167161133466722 Telangana1670461353571016 Bihar164224149722855 Assam150349121610528 Kerala12221687341490 Gujarat119088999083271 Rajasthan109088906851293 Haryana103773816901069 Madhya Pradesh97906743981877 Punjab90032658182646 Chhatisgarh7777541111628 Jharkhand6710052807590 Jammu and Kashmir5971138521951 Uttarakhand3713924810460 Goa2678320844327 Puducherry2142816253431 Tripura2069612956222 Himachal Pradesh11190691997 Chandigarh92566062106 Manipur8430653951 Arunachal Pradesh6851496713 Nagaland5306407910 Meghalaya4356234232 Sikkim2119178923 Mizoram15069490
  Life   Health  17 Aug 2018  Cancer risk with diabetes is higher for women than men

Cancer risk with diabetes is higher for women than men

Published : Aug 17, 2018, 3:55 pm IST
Updated : Aug 17, 2018, 3:55 pm IST

Find out why.

Representational Image. (Photo: Pixabay)
 Representational Image. (Photo: Pixabay)

People with diabetes are more likely to develop certain cancers than those without the condition, and a new analysis suggests that the increased risk is greater for women than for men.

Diabetes and obesity, one of the main causes of the most common form of the disease, are both independent risk factors for a variety of cancers. Some previous research suggests that this may be due at least in part to biological changes caused by these conditions such as high blood sugar levels and chronic inflammation as well as increased production of estrogen in women and decreased testosterone in men.


To see if men and women with diabetes might have different risks of developing cancer, researchers examined data from 47 studies with a total of more than 19.2 million participants.

Compared to people without diabetes, women with diabetes were 27 percent more likely to develop cancer and men were 19 percent more likely to develop cancer, the study found.

While the smaller studies included in this analysis were not controlled experiments designed to prove whether or how diabetes might cause cancer, high blood sugar levels that can accompany diabetes can lead to DNA damage that may cause cancer, said lead study author Toshiaki Ohkuma of the George Institute for Global Health in New South Wales, Australia.


This, of course, holds true for both men and women, Ohkuma said by email. It’s possible women with diabetes have a higher cancer risk than men because women go longer with slightly elevated blood sugar that’s not full-blown diabetes but can still damage cells, Ohkuma said.

“In addition, after diagnosis of diabetes, women are often undertreated or not getting the same level of treatment as men,” Ohkuma added. “This means that cumulative exposure to cancer-causing (high blood sugar) may be longer (and more pronounced) in women than men, and thus women are at greater risk of developing cancer.”

For many cancers that can develop in both women and men, women were more at risk, the researchers report in Diabetologia.


Compared to men with diabetes, women with diabetes were 11 percent more likely to develop kidney cancer, 13 percent more likely to get oral malignancies, 14 percent more likely to get stomach tumors and 15 percent more likely to get leukemia.

Women with diabetes, however, were 12 percent less likely to develop liver cancer than men with diabetes.

To minimize their risk of cancers associated with diabetes, men and women alike should focus on healthy behaviors that can prevent diabetes from developing in the first place, said Dr. Graham Colditz, associate director of prevention and control at the Siteman Cancer Center and Washington University School of Medicine in St. Louis, Missouri.


“Don’t smoke; be physically active; and eat a diet filled with fruits, vegetables and whole grains and low in red and processed meats,” Colditz, who wasn’t involved in the study, said by email. “These behaviors can have health benefits no matter what your weight and even if you also have diabetes.”

Tags: cancer, diabetes, obesity, diseases