Prenatal exposure to pollution harmful

A new study suggests that it leads to emotional problems in children.

Exposure to common air pollutants during pregnancy may predispose children to problems regulating their thoughts, emotions and behaviors later on, according to a new study led by researchers at the Columbia Center for Children’s Environmental Health within Columbia University’s Mailman School of Public Health and New York State Psychiatric Institute. The new study is the first-of-its-kind to examine the effects of early life exposure to a common air pollutant known as PAH (polycyclic aromatic hydrocarbons) on self-regulating behaviours and social competency that incorporates multiple assessment points across childhood. Children with poor self-regulation skills have difficulty managing disruptive thoughts, emotions and impulses; poor social competency limits their ability to get along with others. The study appears in the Journal of Child Psychology and Psychiatry.

PAH are ubiquitous in the environment from emissions from motor vehicles; oil, and coal burning for home heating and power generation; tobacco smoke; and other combustion sources.

Prenatal exposure to PAH has been associated with ADHD; symptoms of anxiety, depression and inattention; and also behavioural disorders, which are all thought to be related to deficits in self-regulation. Lead investigator Amy Margolis, assistant professor of medical psychology in the Department of Psychiatry at Columbia University Medical Center and New York State Psychiatric Institute, and colleagues analysed maternal blood samples and child tests results from 462 mother-child pairs, a subset of CCCEH’s ongoing urban birth cohort study in New York City, from pregnancy through early childhood. Maternal exposure to PAH was determined by presence of DNA-PAH adducts in maternal blood.

The evidence that prenatal exposure to PAH leads to long-term effects on self-regulatory capacities during early and middle childhood suggests that PAH exposure may be an important underlying and contributing factor to the genesis of a range of childhood mental health problems. In terms of a potential mechanism, researchers suggest that prenatal exposure to PAH damages neural circuits that direct motor, attentional and emotional responses. Further deficits in self-regulation may predispose children to becoming engaged in high-risk adolescent behaviors.

“This study indicates that prenatal exposure to air pollution impacts development of self-regulation and as such may underlie the development of many childhood psychopathologies that derive from deficits in self-regulation, such as ADHD, OCD, substance use disorders, and eating disorders,” says Margolis.