Risk of reinfection from Omicron three times higher than any other variant: Study

National daily cases almost doubled on Wednesday, days after countries across the world halted flights to and from southern Africa

Update: 2021-12-03 10:27 GMT
New cases exceeded 11,000 on Thursday, compared with 585 two weeks ago, according to government data. (Photo: PTI)

The risk of reinfection from the omicron coronavirus variant is three times higher than for any previous strain, according to a South African study of infections since the start of the pandemic.

The finding provides evidence of omicron’s “ability to evade immunity from prior infection,” according to the authors, Juliet Pulliam of the South African Center for Epidemiological Modelling and Analysis and Harry Moultrie of the National Center for Communicable Diseases.

The study was based on data collected through South Africa’s health system on about 2.8 million confirmed coronavirus infections between March 2020 and Nov. 27, the authors wrote in an emailed statement. Of those, 35,670 were suspected reinfections.

“Our most urgent priority now is to quantify the extent of omicron’s immune escape for both natural and vaccine-derived immunity, as well as its transmissibility relative to other variants and impact on disease severity,” they wrote.

That strain has rapidly taken hold in Africa’s most-industrialized nation. New cases exceeded 11,000 on Thursday, compared with 585 two weeks ago, according to government data. In Gauteng, the nation’s richest province and its Covid-19 epicenter, each infected person on average is able to pass on the virus to another 2.33, according to the National Institute for Communicable Diseases.

The beta or delta variants spread “primarily from increased transmissibility, rather than immune escape,” according to the research paper, which hasn’t been peer reviewed.

South Africa announced the discovery of a new variant, later named omicron, on Nov. 25 as cases began to spike and the strain spread across the globe. National daily cases almost doubled on Wednesday, days after countries across the world halted flights to and from southern Africa.

“This virus may be similar to delta in its ability to spread or in being contagious,” Anne von Gottberg, a clinical microbiologist at South Africa’s National Institute for Communicable Diseases, said at a briefing on Thursday. “However, it’s the susceptibility of the population that is greater now because previous infection used to protect against delta and now, with omicron, it doesn’t seem to be the case.”

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